Otterbein is an historic residential community in downtown Baltimore, Maryland. Located a few blocks west of the Inner Harbor, Otterbein includes about a dozen blocks from Sharp eastward to Charles and from Conway south to Henrietta.

The neighborhood began in the mid-1800's as a home to those working in the shipping trades. The buildings survived the great fire of 1904 and the area became a destination for European immigrants. Following a gradual decline in the 1950's and 1960's, the neighborhood was renewed beginning in the late 1970's. Today, the community offers a mix of old and new homes that are convenient to the central business district, to public and highway transportation, to two major league stadiums, and to the arts and entertainment venues of adjacent neighborhoods.